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Symptoms of overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Celebrex overdose may include:
Breathing diffic ulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, vomiting

Drug Interactions
If Celebrex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Celebrex with the following:

- ACE-inhibitors (a type of blood pressure and heart medication, including such drugs as Capoten, Vasotec, and Prinivil)
- Blood thinning agents such as Coumadin
- Fluco nazole (Diflucan)
- Furosemide (Lasix)
- Lithium (Eskalith, Lithobid)
- Thiazide diuretics (water pills) such as hydrochlorothiazide and Dyazide

If you take low-dose aspirin t o protect against heart attack, you can continue taking it with Celebrex.

How to Use
You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. CELEBREX capsules come in 2 strengths: 100 mg and 200 mg.

In O steoarthritis, the recommended dose for CELEBREX is 200 mg a day. CELEBREX delivers 24-hour relief from a once-daily dose of 200 mg. Or if preferred, a dose of 100 mg twice a day is available.

In Rheumatoid Arthritis, the recommended dose for CELEBREX is 100 mg to 200 mg, twice a day. CELEBREX provides relief through the day and through the night.

Precautions
Remember to tell your doctor about any stomach ulcers or bleeding you've had in the past. Also alert your doctor if you develop any digestive problems, swelling, or rash.

If you have asthma, use Celebrex with caution. It could trigger an attack, especially if you are also sensitive to aspirin.

If you are taking a steroid medication for your arthritis, do not discontinue it abru ptly when you begin therapy with Celebrex. Celebrex is not a substitute for such drugs.

If you are prone to anemia (loss of red blood cells), make sure the doctor knows about it. Celebrex oc casionally fosters this problem.

The safety and effectiveness of Celebrex have not been tested in children under 18.

Side Effects
More common side effects may include:
- Abdominal pain, diarrhea, headache, indigestion, nausea, respiratory infection, sinus inflammation

Less common side effects may include:
- Ba ck pain, dizziness, gas, insomnia, rash, runny nose, sore throat, swelling

What Is It
Celebrex is a drug that helps relieve pain associated with osteoarthritis and adult rheumatoid arthritis. The reason that Celebrex has become so popular is because it is easier on the stomach than oth er anti-arthritis medication. Celebrex is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis. This medicine is a nonsteroidal anti-inflammatory drug (NSAI D) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and rheumatoid arthritis in adults. Reporting on the 63rd Annual Meeting of the American College of Rheumatology in Decembe r, thirdage.com reported that in analysis of 800 arthritis patients, more than one-third had stopped taking medications because they couldn't handle the stomach pains associated with the drugs.


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